What happens during the innate immune response?

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Information Extraction Results

observations | revealing | mode of interferon antagonism by SARS-CoV-2 (count: 1)
These observations suggest a viral strategy to target the RNA nuclear export activity of RAE1, potentially revealing a mode of interferon antagonism by SARS-CoV-2.
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interferon signal | was over-activated In | COVID-19 conditions (count: 1)
In other COVID-19 conditions, the interferon signal was also over-activated to varying degrees.
we | observed | up-regulation expression of interferon signal genes in COVID-19 (count: 1)
First, we observed up-regulation expression of the interferon signal genes in the COVID-19
SARS-CoV-2 | demonstrates | significant sensitivity to type I interferon treatment (count: 1)
Article Summary: SARS-CoV-2 has similar replication kinetics to SARS-CoV, but demonstrates significant sensitivity to type I interferon treatment.
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impact | is neglected over | researchers toil for anti-viral against COVID-19 (count: 1)
As researchers all over toil hard for an effective anti-viral and vaccine against COVID-19, the psychological impact of the illness is largely neglected.
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anti-viral drugs | included in | case management protocols COVID-19 (count: 1)
Consequently, lopinavir-ritonavir and remdesevir are currently the only anti-viral drugs included in the more severe case management protocols of COVID-19 [10] .
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anti-viral peptides | targeting | 2019-nCoV (count: 1)
These formulations could be used as adjuncts to monotherapy or as combinational therapies with cyclosporine, lopinavirritonavir, interferon beta-1b, ribavirin, remdesivir, monoclonal antibodies, and anti-viral peptides targeting 2019-nCoV. 11 Tocilizumab, a monoclonal antibody that targets the interleukin 6 receptor, has a good safety profile.