| lung macrophage population | was present in | COVID-19 patients (count: 1) | |
|---|---|
| The increased lung macrophage population was present in severe COVID-19 patients.
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| we | identified | macrophage population from COVID-19 patients (count: 1) | |
| Moreover, we identified a novel intermediate macrophage population (group 2), only from the severe COVID-19 patients.
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| macrophage subsets | is in | SARS-CoV-2-infected human lungs (count: 1) | |
| However, little is known regarding the macrophage subsets and their molecular features in SARS-CoV-2-infected human lungs.
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| neutrophil counts | were higher in | non-COVID-19 patients (count: 1) | |
| Compared with COVID-19 patients, the total WBC and neutrophil counts were higher in non-COVID-19 patients.
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| neutrophil-to-lymphocyte ratio | was identified as | risk factor for illness in patients with 2019-nCoV infection (count: 1) | |
| Results: The neutrophil-to-lymphocyte ratio (NLR) was identified as the independent risk factor for severe illness in patients with 2019-nCoV infection.
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| neutrophils | predicted | death of patients with COVID-19 (count: 1) | |
| Elevated high sensitivity troponin, neutrophils and depressed oxygen saturation predicted the rapid death of patients with COVID-19.
-- reference not found! | |
| neutrophil-to-lymphocyte ratio | was identified as | indicator for COVID-19 (count: 1) | |
| Increasing clinical data indicated that the neutrophil-to-lymphocyte ratio (NLR) was identified as a powerful predictive and prognostic indicator for severe COVID-19.
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| leukomonocytes | counts | COVID-19 infection (count: 1) | |
| We propose here that leukomonocytes counts COVID-19 infection and that can update the current COVID-19 diagnosis
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| Inflammatory monocytes | is with | high expression of IL-6 in severe pulmonary syndrome patients of 2019-nCoV (count: 1) | |
| Inflammatory monocytes with high expression of IL-6 in severe pulmonary syndrome patients of 2019-nCoV. (a) Representative density plots showing an analysis of CD14 and CD16 expressions in gated CD45 + monocytes (Gating strategy showing in Extended Data Figure 1a) isolated from peripheral blood in in healthy controls, ICU and non-ICU patients of 2019-nCoV. (b) Representative density plots showing an analysis of GM-CSF and IL-6 expressions in gated CD45 + CD14 + monocyte cells isolated from peripheral blood in healthy controls, in ICU and non-ICU patients of 2019-nCoV. (c) Statistics calculated by the percentage of CD14 + CD16 + subsets from monocytes.
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| eosinophils | assist in | diagnosis of COVID-19 (count: 1) | |
| 17 This indicate that eosinophils could assist in the diagnosis and severity assessment of COVID-19.
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| SARS-CoV-2 | recruiting | macrophages (count: 1) | |
| Immunohistochemistry showed strong presence of CD68 + macrophages were in the tubulointerstitium of these six cases, while moderate numbers of CD8 + T cells were also observed in two cases, whereas, CD4 + T cells and CD56 + natural killer (NK) cells were seldom found in the examined tissues ( Figure 3A, Table 2 ), suggesting that SARS-CoV-2 might cause further tubular damage through recruiting macrophages to infiltrate into the .
-- reference not found! | |
| neutrophil-to-lymphocyte ratio | were higher in | COVID-19 group (count: 1) | |
| Although neutrophil count had no obvious difference, the neutrophil-to-lymphocyte ratio (NLR) were significantly higher in the COVID-19 group
-- COVID-19 early warning score: a multi-parameter screening tool to identify highly suspected patients. medrxiv. 2020-03-08. | |
| SARS-CoV-2 | triggers | cytokine release from monocytes (count: 1) | |
| Our previous work demonstrating that monocytes and macrophages can produce pro-inflammatory cytokine during murine hepatitis virus strain-3 infection, 30, 31 and whether SARS-CoV-2 also triggers cytokine release from monocytes and macrophages in COVID-19 patients need further investigation and such work is in progress in our hospital.
-- Reduction and Functional Exhaustion of T Cells in Patients with Coronavirus Disease 2019 (COVID-19). medrxiv. 2020-02-20. | |
| macrophages | revealing | clearing attributable to SARS-CoV-2 (count: 1) | |
| Desquamated pneumocytes, multinucleated syncytial cells, and hyaline material were not appreciated; however, occasional alveolar macrophages revealing nuclear clearing or intranuclear cytopathic inclusions attributable to SARS-CoV-2 were easily found (Fig.
-- reference not found! | |